When it may be considered
- Selected cases of ankle osteoarthritis.
- Tendinopathies.
- Osteochondral lesions, as an adjunctive treatment in specific cases.
Your recovery, step by step
A medical assessment helps establish how PRP may benefit you and integrate it into a treatment and rehabilitation plan tailored to your needs. The aim is to improve your symptoms and your ability to take part in the activities that matter to you, while monitoring your progress.
Distinguishing joint, cartilage and tendon
Ankle osteoarthritis, an osteochondral lesion and a tendinopathy are different problems. Evidence for one indication cannot automatically be applied to the others.
What we know about ankle osteoarthritis
A randomised trial involving 100 patients found no significant difference between two PRP injections and saline at 26 weeks. This result does not support presenting PRP as a treatment with established effectiveness for ankle osteoarthritis.
An individual decision with alternatives
Stability, alignment, loading and previous treatments are reviewed before considering PRP. The consultation should clarify the goal, the degree of uncertainty and the relevant non-surgical or surgical options.
Sources and further reading
Paget and colleagues, JAMA, 2021
Sources consulted on 19 October 2026. General information; treatment indications are determined during the consultation.